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Due to its natural origin, Orthoss® displays a high degree of similarity to human bone. This accounts for the excellent osteoconductivity of Orthoss® and allows the participation of Orthoss® in the natural remodelling process of the bone. Synthetic bone replacement materials, such as Tricalciumphosphate(TCP) or glass granules, are different from bone in their structure and composition.
Allogenic bone (bone bank) is frequently used for bone replacement and regeneration. The application of autologous bone is limited by its availability and additional stress to the patient through secondary operations and donor site morbidity. Homologous bone carries immunological risks, as well as the risk of infection from bone in their construction and composition are not incorporated during the natural reconstruction process of the bone. With the development of Orthoss®, an alternative bone replacement material is available, in which the natural inorganic, hydroxyapatite-based bone structure is maintained. Orthoss® is supporting the natural remodelling process of the bone by offering a matrix for osteoblasts.
Orthoss shows best clinical results when it is used as a volume expander for autologous bone in different orthopaedic procedures.
In the production of Orthoss®, proteins from bovine bone are removed in a patented procedure, and the original properties of the natural mineral structure remain largely unchanged.
A special procedure has been developed for the production of Orthoss® that makes the deproteinization of bovine bone possible. The remaining mineral bone matrix exists in pure, unchanged form.
Removal of proteins trough a combination of heat treatment and aggressive chemical methods, where by the risks of disease transmission or immunological reactions are eliminated.
Quality safety assurance according to the international standards (ISO 9001 / ISO 13485), which is controlled once a year by independent experts. Constant, high product quality, which improves the prognosis.
Full pre-clinical and clinical testing since 1985 on more than3 Million patients in Orthopedics (Orthoss®) and Dental (Geistlich Bio-Oss®). Orthoss is a CE-marked product.